Powder: -20°C for 3 years | In solvent: -80°C for 1 year
FGH31 (Compound 24), a dopamine D4 agonist, exhibits potent and selective GRK2-dependency with a K i of 1.6 nM and partially activates β-arrestin [1].
説明 | FGH31 (Compound 24), a dopamine D4 agonist, exhibits potent and selective GRK2-dependency with a K i of 1.6 nM and partially activates β-arrestin [1]. |
ターゲット&IC50 | Dopamine D4 receptor:1.6 nM (Ki) |
In vitro | Compound FGH31 (50 μM) exhibits a rate of decline in rat liver microsomes comparable to that of Imipramine [1]. Additionally, there is no evidence of P-glycoprotein (P-gp) mediated transport of FGH31 (50 μM, 4 h) in Caco-2 cells [1]. |
分子量 | 520.66 |
分子式 | C33H36N4O2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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FGH31 GPCR/G Protein Neuroscience Dopamine Receptor Inhibitor inhibitor inhibit