Powder: -20°C for 3 years | In solvent: -80°C for 1 year
G12Si-5 is a covalent inhibitor of the K-RasG12S mutant with a Ki value of 26 μM. G12Si-5 binds to the S-IIP structural domain and inhibits oncogenic signalling. g12Si-5 reduces ERK phosphorylation levels in KRAS G12S mutant cells.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約10-14 週間 | ¥ 349,000 |
50 mg | 約10-14 週間 | ¥ 454,500 |
100 mg | 約10-14 週間 | ¥ 574,000 |
説明 | G12Si-5 is a covalent inhibitor of the K-RasG12S mutant with a Ki value of 26 μM. G12Si-5 binds to the S-IIP structural domain and inhibits oncogenic signalling. g12Si-5 reduces ERK phosphorylation levels in KRAS G12S mutant cells. |
分子量 | 574.05 |
分子式 | C31H29ClFN5O3 |
CAS No. | 2946593-46-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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G12Si-5 2946593-46-8 Inhibitor inhibitor inhibit