Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ganglioside GM2 asialo (asialo- GM2) is a glycosphingolipid containing three monosaccharide residues and a fatty acid of variable chain length but lacking the sialic acid residue present on ganglioside M2. Asialo-GM2 levels are low-to-undetectable in normal human brain, but it accumulates in the brain of patients with Tay-Sachs and Sandhoff disease, which are neurodegenerative disorders characterized by deficiency of lysosomal β-hexosaminidase A and B, respectively. It also binds to various bacteria, including Pseudomonas isolates derived from cystic fibrosis patients. Asialo-GM2 mixture contains ganglioside GM2 asialo molecular species with fatty acyl chains of variable lengths.
説明 | Ganglioside GM2 asialo (asialo- GM2) is a glycosphingolipid containing three monosaccharide residues and a fatty acid of variable chain length but lacking the sialic acid residue present on ganglioside M2. Asialo-GM2 levels are low-to-undetectable in normal human brain, but it accumulates in the brain of patients with Tay-Sachs and Sandhoff disease, which are neurodegenerative disorders characterized by deficiency of lysosomal β-hexosaminidase A and B, respectively. It also binds to various bacteria, including Pseudomonas isolates derived from cystic fibrosis patients. Asialo-GM2 mixture contains ganglioside GM2 asialo molecular species with fatty acyl chains of variable lengths. |
別名 | Ganglioside GM2 Asialo Mixture |
分子量 | 1093.444 |
分子式 | C56H104N2O18 |
CAS No. | 35960-33-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Chloroform:Methanol:H2O (2:1:0.1): Soluble
You can also refer to dose conversion for different animals. 詳細
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Ganglioside GM2 Asialo Mixture 35960-33-9 Ganglioside GM-2 Asialo Mixture Inhibitor inhibitor inhibit