Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GlcN-6-P Synthase-IN-1 (Compound 4d) is a potent inhibitor of Glucosamine-6-phosphate (GlcN-6-P) synthase, with an IC50 of 3.47 μM. This compound demonstrates remarkable antimicrobial activity and exhibits excellent penetration in the central nervous system. Additionally, GlcN-6-P Synthase-IN-1 is capable of inhibiting cytochrome P450, specifically the CYP3A4 isoform [1].
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 349,000 |
50 mg | 約6-8 週間 | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
説明 | GlcN-6-P Synthase-IN-1 (Compound 4d) is a potent inhibitor of Glucosamine-6-phosphate (GlcN-6-P) synthase, with an IC50 of 3.47 μM. This compound demonstrates remarkable antimicrobial activity and exhibits excellent penetration in the central nervous system. Additionally, GlcN-6-P Synthase-IN-1 is capable of inhibiting cytochrome P450, specifically the CYP3A4 isoform [1]. |
In vitro | GlcN-6-P Synthase-IN-1 (Compound 4d) displays antimicrobial properties, as evidenced by its minimum inhibitory concentration (MIC) values. These values are 1 ± 0.15 μg/mL against S. aureus, 0.5 ± 0.15 μg/mL against B. subtilis, and 4 ± 0.33 μg/mL for both C. albicans and A. oryzae, indicating its effective inhibition of these microorganisms [1]. |
分子量 | 391.49 |
分子式 | C20H21N7S |
CAS No. | 2447602-44-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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GlcN-6-P Synthase-IN-1 2447602-44-8 Inhibitor inhibitor inhibit