Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Compound 3e (hCAIX/XII-IN-7) is a potent inhibitor of human carbonic anhydrase (hCA) isozymes IX and XII, displaying inhibitory constants (Kis) of 503.7 nM for hCA IX and 59 nM for hCA XII, while also showing activity against hCA I and II with Kis of 3.2 nM and 9.2 nM, respectively. It holds potential for research into hypoxic tumors [1].
説明 | Compound 3e (hCAIX/XII-IN-7) is a potent inhibitor of human carbonic anhydrase (hCA) isozymes IX and XII, displaying inhibitory constants (Kis) of 503.7 nM for hCA IX and 59 nM for hCA XII, while also showing activity against hCA I and II with Kis of 3.2 nM and 9.2 nM, respectively. It holds potential for research into hypoxic tumors [1]. |
ターゲット&IC50 | hCA IX:3.2 nM (Ki), hCA I:503.7 nM (Ki), hCA XII:9.2 nM (Ki), hCA II:59 nM (Ki) |
分子量 | 382.4 |
分子式 | C17H14N6O3S |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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hCAIX/XII-IN-7 Metabolism Carbonic Anhydrase Inhibitor inhibitor inhibit