Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HDAC-IN-27 is a potent and orally active inhibitor of HDAC Class I (0.43 nM - 3.01 nM for HDAC1-3). HDAC-IN-27 shows activity against anti-acute myeloid leukemia (AML).
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約10-14 週間 | ¥ 349,000 |
50 mg | 約10-14 週間 | ¥ 454,500 |
100 mg | 約10-14 週間 | ¥ 574,000 |
説明 | HDAC-IN-27 is a potent and orally active inhibitor of HDAC Class I (0.43 nM - 3.01 nM for HDAC1-3). HDAC-IN-27 shows activity against anti-acute myeloid leukemia (AML). |
In vitro | In wild-type p53 MV4-11 cells, HDAC-IN-27 (11h) promotes pro-caspase-3 cleavage, triggers apparent apoptotic cell death, and increases the sub-G1 cell population. Conversely, it induces G2/M arrest in HL60 cells without showing signs of apoptosis [1]. |
分子量 | 350.41 |
分子式 | C20H22N4O2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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HDAC-IN-27 Inhibitor inhibitor inhibit