Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HDAC-IN-46 (compound 12c) is a potent inhibitor of HDAC that acts on HDAC1 (IC50: 0.21 μM) and HDAC6 (IC50: 0.021 μM). HDAC-IN-46 upregulates p-p38 and downregulates Bcl-xL and cyclin D1 in MDA-MB-231 cells. HDAC-IN-46 can block the cell cycle in G2 phase and induce apoptosis. HDAC-IN-46 can be used in triple negative breast cancer (TNBC) studies.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約8-10 週間 | ¥ 491,500 |
50 mg | 約8-10 週間 | ¥ 639,500 |
100 mg | 約8-10 週間 | ¥ 808,000 |
説明 | HDAC-IN-46 (compound 12c) is a potent inhibitor of HDAC that acts on HDAC1 (IC50: 0.21 μM) and HDAC6 (IC50: 0.021 μM). HDAC-IN-46 upregulates p-p38 and downregulates Bcl-xL and cyclin D1 in MDA-MB-231 cells. HDAC-IN-46 can block the cell cycle in G2 phase and induce apoptosis. HDAC-IN-46 can be used in triple negative breast cancer (TNBC) studies. |
分子量 | 438.53 |
分子式 | C22H30N8O2 |
CAS No. | 2562386-85-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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HDAC-IN-46 2562386-85-8 Inhibitor inhibitor inhibit