Powder: -20°C for 3 years | In solvent: -80°C for 1 year
IMMH 010 maleate (YPD-30 maleate) is an orally available programmed cell death ligand 1 inhibitor with potential antitumor activity for the study of neurological disorders and advanced malignant solid tumors.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 45,000 | |||
5 mg | 在庫あり | ¥ 111,000 | |||
10 mg | 在庫あり | ¥ 159,000 | |||
25 mg | 在庫あり | ¥ 248,000 | |||
50 mg | 在庫あり | ¥ 342,000 | |||
100 mg | 在庫あり | ¥ 452,500 |
説明 | IMMH 010 maleate (YPD-30 maleate) is an orally available programmed cell death ligand 1 inhibitor with potential antitumor activity for the study of neurological disorders and advanced malignant solid tumors. |
In vitro | IMMH-010 maleate (YPD-30) is an ester prodrug of YPD-29B, which is an effective small-molecule inhibitor targeting hPD-L1 in vitro[1]. |
In vivo | IMMH-010 maleate (YPD-30; 2.5, 5, and 10 mg/kg; oral administration, twice weekly) significantly delayed tumor progression in mice compared to the vehicle group in a dose-dependent manner. The tumor growth inhibition rates (TGI) were 40.5% (2.5 mg/kg), 60.9% (5 mg/kg), and 67.9% (10 mg/kg), respectively[1]. |
別名 | YPD-30 maleate |
分子量 | 756.04 |
分子式 | C36H36BrClN2O9 |
CAS No. | 2541982-47-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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IMMH 010 maleate 2541982-47-0 Apoptosis Cell Cycle/Checkpoint Immunology/Inflammation PD-1/PD-L1 YPD-30 maleate IMMH010maleate Inhibitor inhibitor inhibit