Powder: -20°C for 3 years | In solvent: -80°C for 1 year
IMP-1700 is an inhibitor of bacterial DNA repair.1It potentiates the activity of the quinolone antibiotic ciprofloxacin against methicillin-resistantS. aureus(MRSA) with a combination index value of 0.7. IMP-1700 inhibits the ciprofloxacin-induced bacterial SOS response, a process that repairs DNA damage, in a reporter assay in a concentration-dependent manner. It is also active againstE. coli, as well as methicillin-resistant and -sensitive S. aureus, when used alone (EC50s = 0.5, 0.21, and 3.8 μM, respectively).
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
5 mg | 約 35 days | ¥ 53,500 |
10 mg | 約 35 days | ¥ 90,500 |
25 mg | 約 35 days | ¥ 209,500 |
説明 | IMP-1700 is an inhibitor of bacterial DNA repair.1It potentiates the activity of the quinolone antibiotic ciprofloxacin against methicillin-resistantS. aureus(MRSA) with a combination index value of 0.7. IMP-1700 inhibits the ciprofloxacin-induced bacterial SOS response, a process that repairs DNA damage, in a reporter assay in a concentration-dependent manner. It is also active againstE. coli, as well as methicillin-resistant and -sensitive S. aureus, when used alone (EC50s = 0.5, 0.21, and 3.8 μM, respectively). |
分子量 | 534.53 |
分子式 | C25H22F4N4O3S |
CAS No. | 1458674-25-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF: Slightly soluble
DMSO: Slightly soluble
You can also refer to dose conversion for different animals. 詳細
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IMP-1700 1458674-25-3 IMP 1700 IMP1700 Inhibitor inhibitor inhibit