Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JNK3 inhibitor-2 is a potent and selective JNK3 inhibitor. The IC50 values of JNK3 inhibitor-2 for JNK1, JNK2, JNK3 are >100, >100, 0.25 μM, respectively. JNK3 inhibitor-2 also inhibits DDR1 and EGFR (T790M, L858R) [1].
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 349,000 |
50 mg | 約6-8 週間 | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
説明 | JNK3 inhibitor-2 is a potent and selective JNK3 inhibitor. The IC50 values of JNK3 inhibitor-2 for JNK1, JNK2, JNK3 are >100, >100, 0.25 μM, respectively. JNK3 inhibitor-2 also inhibits DDR1 and EGFR (T790M, L858R) [1]. |
In vitro | Compound J46, also known as JNK3 inhibitor-2, demonstrates selective inhibition, showing 30% inhibition of JNK2α2 at a concentration of 30 μM and 60% at 100 μM. Additionally, it exhibits potent inhibitory effects on DDR1 and EGFR (T790M, L858R), with IC50 values of 0.16 μM and 0.37 μM, respectively [1]. |
分子量 | 314.34 |
分子式 | C20H14N2O2 |
CAS No. | 2366264-18-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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JNK3 inhibitor-2 2366264-18-6 Inhibitor inhibitor inhibit