Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Keap1-Nrf2-IN-15 (Compound 24a) is a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, displaying IC50 values of 77 nM in a fluorescence polarization (FP) assay and 2.5 nM in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay [1].
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約8-10 週間 | ¥ 349,000 |
50 mg | 約8-10 週間 | ¥ 454,500 |
100 mg | 約8-10 週間 | ¥ 574,000 |
説明 | Keap1-Nrf2-IN-15 (Compound 24a) is a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, displaying IC50 values of 77 nM in a fluorescence polarization (FP) assay and 2.5 nM in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay [1]. |
In vitro | Keap1-Nrf2-IN-15 (Compound 24a) binds to Keap1 protein [1]. When applied at concentrations of 10 and 100 μM for 24 hours, Keap1-Nrf2-IN-15 notably induces the expression of Nrf2 target genes (HMOX1, GSTM3, NQO1) in NCM460D cells [1]. |
分子量 | 801.84 |
分子式 | C39H35N3O12S2 |
CAS No. | 2456295-45-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Keap1-Nrf2-IN-15 2456295-45-5 Inhibitor inhibitor inhibit