Powder: -20°C for 3 years | In solvent: -80°C for 1 year
KMG-104 is a fluorescent magnesium (Mg2+) probe known for its exceptional selectivity. It has been extensively utilized to investigate the mobilization of Mg2+ in the cytoplasm across different cell types.
説明 | KMG-104 is a fluorescent magnesium (Mg2+) probe known for its exceptional selectivity. It has been extensively utilized to investigate the mobilization of Mg2+ in the cytoplasm across different cell types. |
In vitro | KMG-104 is an effective compound for confocal laser scanning microscopy, characterized by its excitation at 490 nm and fluorescence emission around 510 nm. Its fluorescence intensity correlates positively with magnesium ([Mg]) concentration, while remaining inert to sodium, potassium, and calcium ions. This specificity is evidenced by a dissociation constant (Kd) for Mg at 3 mM, indicating its proficiency in exclusively tracking [Mg] changes under physiological conditions. In experimental setups, PC12 cells infused with KMG-104 and the calcium indicator fura-2 have facilitated the exploration of intracellular magnesium in cellular components such as endoplasmic reticulums (ERs), mitochondria, and Mg-ATP complexes. |
分子量 | 435.339 |
分子式 | C23H11F2NO6 |
CAS No. | 852057-94-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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KMG-104 852057-94-4 KMG 104 KMG104 Inhibitor inhibitor inhibit