Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LDN-211904 oxalate (compound 32), a potent and selective EphB3 inhibitor, demonstrates an IC50 of 0.079 μM and shows good metabolic stability in mouse liver microsomes. When combined with cetuximab, it may effectively inhibit STAT3-activated CSC stemness and cetuximab resistance in CRC [1] [2].
説明 | LDN-211904 oxalate (compound 32), a potent and selective EphB3 inhibitor, demonstrates an IC50 of 0.079 μM and shows good metabolic stability in mouse liver microsomes. When combined with cetuximab, it may effectively inhibit STAT3-activated CSC stemness and cetuximab resistance in CRC [1] [2]. |
分子量 | 444.87 |
分子式 | C21H21ClN4O5 |
CAS No. | 1198408-78-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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LDN-211904 1198408-78-4 LDN211904 LDN 211904 Inhibitor inhibitor inhibit