Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LSD1/2-IN-3 is a selective inhibitor of lysine-specific demethylase 1 ( LSD1 ) with a Ki value of 11 nM rather than 7 μM for LSD2. There is aberrant expression of LSD1 in tumor stem cells, LSD1/2-IN-1 inhibits LSD1 cell proliferation [1].
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約10-14 週間 | ¥ 349,000 |
50 mg | 約10-14 週間 | ¥ 454,500 |
100 mg | 約10-14 週間 | ¥ 574,000 |
説明 | LSD1/2-IN-3 is a selective inhibitor of lysine-specific demethylase 1 ( LSD1 ) with a Ki value of 11 nM rather than 7 μM for LSD2. There is aberrant expression of LSD1 in tumor stem cells, LSD1/2-IN-1 inhibits LSD1 cell proliferation [1]. |
In vitro | LSD1/2-IN-3 (compound 8c) inhibits proliferation of the T-cell acute lymphoblastic leukemia (T-ALL) with IC 50 s of 25 μM (CCRF-CEM) and 27 μM (Jurkat), respectively, while not inhibits the human normal fibroblast cell line WI-38 [1]. |
分子量 | 248.07 |
分子式 | C9H8BrF2N |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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LSD1/2-IN-3 Inhibitor inhibitor inhibit