Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LY487379 is a selective human mGluR2 positive allosteric modulator (PAM). lY487379 enhances glutamate-stimulated [35 S] GTPγS binding to mGlu2 receptors (EC50: 1.7 μM) and mGlu3 receptors (EC50>10 μM). lY487379 induces cognitive flexibility and induces behavioural inhibition in a rat model. LY487379 can be used to study schizophrenia.
説明 | LY487379 is a selective human mGluR2 positive allosteric modulator (PAM). lY487379 enhances glutamate-stimulated [35 S] GTPγS binding to mGlu2 receptors (EC50: 1.7 μM) and mGlu3 receptors (EC50>10 μM). lY487379 induces cognitive flexibility and induces behavioural inhibition in a rat model. LY487379 can be used to study schizophrenia. |
分子量 | 452.45 |
分子式 | C21H19F3N2O4S |
CAS No. | 353231-17-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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LY487379 353231-17-1 Others Inhibitor inhibitor inhibit