Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Magainin 2, a cationic peptide derived from the African clawed frog (X. laevis) skin, exhibits host defense and antimicrobial properties. This compound effectively inhibits a range of pathogens, including E. coli, K. pneumoniae, S. epidermidis, S. aureus bacteria, and C. albicans fungus, with minimum inhibitory concentrations (MICs) of 5, 10, 10, 50, and 80 µg/ml, respectively. Additionally, at a concentration of 20 µM, Magainin 2 significantly reduces the germination and tube elongation in kiwi fruit pollen. It also curtails viral replication in Vero cells infected by herpes simplex virus 1 (HSV-1) or HSV-2, with half-maximal effective concentrations (EC50s) of 22.16 and 19.8 µM, respectively, while demonstrating low toxicity to these cells, shown by a 50% cytotoxic concentration (CC50) greater than 100 µM.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
500 μg | お問い合わせ | ¥ 62,000 |
1 mg | お問い合わせ | ¥ 114,000 |
5 mg | お問い合わせ | ¥ 275,500 |
10 mg | お問い合わせ | ¥ 399,500 |
説明 | Magainin 2, a cationic peptide derived from the African clawed frog (X. laevis) skin, exhibits host defense and antimicrobial properties. This compound effectively inhibits a range of pathogens, including E. coli, K. pneumoniae, S. epidermidis, S. aureus bacteria, and C. albicans fungus, with minimum inhibitory concentrations (MICs) of 5, 10, 10, 50, and 80 µg/ml, respectively. Additionally, at a concentration of 20 µM, Magainin 2 significantly reduces the germination and tube elongation in kiwi fruit pollen. It also curtails viral replication in Vero cells infected by herpes simplex virus 1 (HSV-1) or HSV-2, with half-maximal effective concentrations (EC50s) of 22.16 and 19.8 µM, respectively, while demonstrating low toxicity to these cells, shown by a 50% cytotoxic concentration (CC50) greater than 100 µM. |
別名 | MG2 |
分子量 | 2466.90 |
分子式 | C114H180N30O29S.XCF3COOH |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/ml
DMF: 5 mg/ml
PBS pH 7.2: 5 mg/ml
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Magainin 2 TFA MG2 Inhibitor inhibitor inhibit