Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MK-28 is a selective PERK agonist that reduces toxicity and prolongs survival in a Huntington's disease model.MK-28 has a significant killing effect on MK28 gastric cancer cells.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 23,000 | |||
5 mg | 在庫あり | ¥ 57,000 | |||
10 mg | 在庫あり | ¥ 91,000 | |||
25 mg | 在庫あり | ¥ 176,000 | |||
50 mg | 在庫あり | ¥ 266,500 | |||
100 mg | 在庫あり | ¥ 397,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 62,500 |
説明 | MK-28 is a selective PERK agonist that reduces toxicity and prolongs survival in a Huntington's disease model.MK-28 has a significant killing effect on MK28 gastric cancer cells. |
In vitro | In STHdhQ111/111 cells, MK-28 (0-100 μM; 48 h) rescued cells from ER stress-induced apoptosis[1]. |
In vivo | In R6/2 mice, MK-28 (1 mg/kg; IP, daily for 28 days) increased the survival rate[1]. |
分子量 | 396.44 |
分子式 | C24H20N4O2 |
CAS No. | 864388-65-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (25.22 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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MK-28 864388-65-8 Apoptosis Immunology/Inflammation Antiviral PERK Inhibitor inhibitor inhibit