keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MTIC is the active metabolite of Temozolomide (TMZ) with anticancer and antitumor activity and is used in the study of melanoma.3'-Sialyllactose (3'-SL) sodium is a prebiotic with anti-inflammatory activity.
説明 | MTIC is the active metabolite of Temozolomide (TMZ) with anticancer and antitumor activity and is used in the study of melanoma.3'-Sialyllactose (3'-SL) sodium is a prebiotic with anti-inflammatory activity. |
In vivo | MTIC was quantified in plasma of cancer patients (n=12) within 0.25-12 h after oral administration of temozolomide at 150 mg/m2. The mean maximum plasma concentration (Cmax) was 211 ng/ml which was observed at a mean Tmax of 1.88 h post dose. MTIC disappeared rapidly from plasma with an apparent in vivo half-life (t1/2) of 1.9 h similar to that of temozolomide[1]. |
別名 | NSC 407347 |
分子量 | 168.16 |
分子式 | C5H8N6O |
CAS No. | 3413-72-7 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 20 mg/mL (118.93 mM), Sonication is recommended.
Methanol: Slightly soluble, Heating is recommended.
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
MTIC 3413-72-7 Metabolism Drug Metabolite NSC407347 NSC-407347 NSC 407347 Inhibitor inhibitor inhibit