Powder: -20°C for 3 years | In solvent: -80°C for 1 year
N-Arachidonoyl taurine is an arachidonoyl amino acid. It is oxygenated by 12(S)- and 15(S)-lipoxygenase and is converted to 12-HETE-taurine (12-HETE-T) in murine resident peritoneal macrophages. N-Arachidonoyl taurine is an activator of the transient receptor potential vanilloid (TRPV) channels TRPV1 and TRPV4 (EC50s = 28 and 21 μM, respectively). It increases calcium flux in HIT-T15 pancreatic β-cells and INS-1 rat islet cells when used at a concentration of 10 μM and increases insulin secretion from 832/13 INS-1 pancreatic β-cells. The levels of N-arachidonoyl taurine are changed in mouse brain following administration of δ9-tetrahydrocannabinol (δ9-THC).
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
500 μg | 約 35 days | ¥ 25,000 |
1 mg | 約 35 days | ¥ 45,500 |
5 mg | 約 35 days | ¥ 190,500 |
10 mg | 約 35 days | ¥ 330,500 |
説明 | N-Arachidonoyl taurine is an arachidonoyl amino acid. It is oxygenated by 12(S)- and 15(S)-lipoxygenase and is converted to 12-HETE-taurine (12-HETE-T) in murine resident peritoneal macrophages. N-Arachidonoyl taurine is an activator of the transient receptor potential vanilloid (TRPV) channels TRPV1 and TRPV4 (EC50s = 28 and 21 μM, respectively). It increases calcium flux in HIT-T15 pancreatic β-cells and INS-1 rat islet cells when used at a concentration of 10 μM and increases insulin secretion from 832/13 INS-1 pancreatic β-cells. The levels of N-arachidonoyl taurine are changed in mouse brain following administration of δ9-tetrahydrocannabinol (δ9-THC). |
分子量 | 411.6 |
分子式 | C22H37NO4S |
CAS No. | 119959-65-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF: 10 mg/mL
DMSO: 20 mg/mL
PBS (pH 7.2): 1.5 mg/mL
You can also refer to dose conversion for different animals. 詳細
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N-Arachidonoyl Taurine 119959-65-8 NArachidonoyl Taurine N Arachidonoyl Taurine Inhibitor inhibitor inhibit