store at low temperature
store at -80°C
Naxitamab (Hu3F8) is a humanized monoclonal antibody against GD2 (hu3F8). Naxitamab has antitumor activity and can be used to study neuroblastoma, osteosarcoma, and other GD2-positive cancers.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 43,500 |
5 mg | 在庫あり | ¥ 109,500 |
10 mg | 在庫あり | ¥ 181,000 |
25 mg | 在庫あり | ¥ 271,000 |
50 mg | 在庫あり | ¥ 365,000 |
100 mg | 在庫あり | ¥ 489,000 |
説明 | Naxitamab (Hu3F8) is a humanized monoclonal antibody against GD2 (hu3F8). Naxitamab has antitumor activity and can be used to study neuroblastoma, osteosarcoma, and other GD2-positive cancers. |
ターゲット&IC50 | LAN1:5.1 μg/mL |
In vitro |
Naxitamab (Hu3F8; 72 h) exhibits cytotoxicity against the neuroblastoma cell line LAN-1, with an EC50 value of 5.1 μg/mL[1]. Naxitamab (0.1-1 μg/mL; 4 h; peripheral blood mononuclear cells (PBMC) and polymorphonuclear leukocytes (PMN)) demonstrates antibody-dependent cell-mediated cytotoxic effects (ADCC)[1]. |
In vivo | In athymic nude mice with LAN-1 xenografts, Naxitamab (Hu3F8; 100 mg/kg; intravenous; twice a week for 4 weeks) inhibits tumor growth in neuroblastoma xenografts[1]. |
別名 | Naxitamab-gqgk, Humanized 3F8, Hu3F8 |
分子量 | N/A |
CAS No. | 1879925-92-4 |
store at low temperature
store at -80°C
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Naxitamab 1879925-92-4 Others Naxitamab-gqgk Humanized 3F8 Hu3F8 Inhibitor inhibitor inhibit