Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NCI-006 is a potent new inhibitor of lactate dehydrogenase (LDH) that disrupts tumor growth in mice. LDH inhibition slows tumor growth but rapidly redirects pyruvate to support mitochondrial metabolism. Inhibiting both mitochondrial complex 1 and LDH suppresses metabolic plasticity of glycolytic tumors in vivo, significantly prolonging tumor growth inhibition.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約10-14 週間 | ¥ 521,000 |
50 mg | 約10-14 週間 | ¥ 684,000 |
100 mg | 約10-14 週間 | ¥ 918,000 |
説明 | NCI-006 is a potent new inhibitor of lactate dehydrogenase (LDH) that disrupts tumor growth in mice. LDH inhibition slows tumor growth but rapidly redirects pyruvate to support mitochondrial metabolism. Inhibiting both mitochondrial complex 1 and LDH suppresses metabolic plasticity of glycolytic tumors in vivo, significantly prolonging tumor growth inhibition. |
分子量 | 650.74 |
分子式 | C31H24F2N4O4S3 |
CAS No. | 1964516-64-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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NCI-006 1964516-64-0 NCATS-SM 1440 NCI 006 NCI006 NCATS-SM-1440 Inhibitor inhibitor inhibit