Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NLRP3-IN-8 (compound 27), an orally active NLRP3 inflammasome inhibitor, directly binds to its target with an IC50 of 1.23 μM for IL-1β inhibition. It demonstrates robust metabolic stability in liver microsomes (t1/2 = 138.63 min) and exhibits minimal toxicity (against L02: IC50 > 100 μM) [1].
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約10-14 週間 | ¥ 349,000 |
50 mg | 約10-14 週間 | ¥ 454,500 |
100 mg | 約10-14 週間 | ¥ 574,000 |
説明 | NLRP3-IN-8 (compound 27), an orally active NLRP3 inflammasome inhibitor, directly binds to its target with an IC50 of 1.23 μM for IL-1β inhibition. It demonstrates robust metabolic stability in liver microsomes (t1/2 = 138.63 min) and exhibits minimal toxicity (against L02: IC50 > 100 μM) [1]. |
分子量 | 420.41 |
分子式 | C23H20N2O6 |
CAS No. | 2768650-56-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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NLRP3-IN-8 2768650-56-0 Inhibitor inhibitor inhibit