Powder: -20°C for 3 years | In solvent: -80°C for 1 year
p38 MAPK inhibitor IV is an ATP-competitive inhibitor of p38 MAP kinases with IC50 values of 0.13, 0.55, 5.47, and 8.63 μM for p38α, p38β, p38x, and p38δ, respectively, in vitro.[1] It also inhibits LPS-induced TNF-α and IL-1β cytokine production (IC50s = 22 and 44 nM, respectively) in human peripheral blood mononuclear cells.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
5 mg | 約 35 days | ¥ 35,500 |
10 mg | 約 35 days | ¥ 66,000 |
25 mg | 約 35 days | ¥ 155,000 |
説明 | p38 MAPK inhibitor IV is an ATP-competitive inhibitor of p38 MAP kinases with IC50 values of 0.13, 0.55, 5.47, and 8.63 μM for p38α, p38β, p38x, and p38δ, respectively, in vitro.[1] It also inhibits LPS-induced TNF-α and IL-1β cytokine production (IC50s = 22 and 44 nM, respectively) in human peripheral blood mononuclear cells. |
ターゲット&IC50 | p38β:0.55 μM (IC50), p38α:0.13 μM (IC50), p38χ:5.47 μM (IC50), p38δ:8.63 μM (IC50) |
別名 | p38 MAPK Inhibitor IV |
分子量 | 456.94 |
分子式 | C12H4Cl6O4S |
CAS No. | 1638-41-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 2.5 mg/mL
DMF: 2 mg/mL
You can also refer to dose conversion for different animals. 詳細
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p38 MAP Kinase Inhibitor IV 1638-41-1 p-38 MAP Kinase Inhibitor IV p38 MAPK Inhibitor IV Inhibitor inhibitor inhibit