keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
p53 tumor suppressor fragment (232-240) is a peptide with the sequence H2N-Lys-Tyr-Met-Cys-Asn-Ser-Ser-Cys-Met-OH, MW= 1066.3. p53 is a tumor suppressor protein that in humans is encoded by the TP53 gene. p53 is crucial in multicellular organisms, where it regulates the cell cycle and, thus, functions as a tumor suppressor that is involved in preventing cancer.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | お問い合わせ | ¥ 11,500 |
5 mg | お問い合わせ | ¥ 33,000 |
10 mg | お問い合わせ | ¥ 54,000 |
25 mg | お問い合わせ | ¥ 75,500 |
説明 | p53 tumor suppressor fragment (232-240) is a peptide with the sequence H2N-Lys-Tyr-Met-Cys-Asn-Ser-Ser-Cys-Met-OH, MW= 1066.3. p53 is a tumor suppressor protein that in humans is encoded by the TP53 gene. p53 is crucial in multicellular organisms, where it regulates the cell cycle and, thus, functions as a tumor suppressor that is involved in preventing cancer. |
In vitro | p53 has been described as 'the guardian of the genome' because of its role in conserving stability by preventing genome mutation. p53 has many mechanisms of anticancer function and plays a role in apoptosis, genomic stability, and inhibition of angiogenesis. In its anti-cancer role, p53 works through several mechanisms: It can activate DNA repair proteins when DNA has sustained damage. It can induce growth arrest by holding the cell cycle at the G1/S regulation point on DNA damage recognition. It can initiate apoptosis, the programmed cell death if DNA damage proves to be irreparable [1][2][3]. |
分子量 | 1066.3 |
分子式 | C41H67N11O14S4 |
CAS No. | TP2281 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: ≥53.3mg/mL
You can also refer to dose conversion for different animals. 詳細
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