keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PAO-Nap is a chemically modified version of PAO, in which a naphthalimide fluorophore is attached to the compound using a linker called aminocaproic acid. This modified compound, PAO-Nap, exhibits a selective targeting of thioredoxin reductase, leading to the induction of apoptosis in HL-60 cells through oxidative stress mechanisms[1].
説明 | PAO-Nap is a chemically modified version of PAO, in which a naphthalimide fluorophore is attached to the compound using a linker called aminocaproic acid. This modified compound, PAO-Nap, exhibits a selective targeting of thioredoxin reductase, leading to the induction of apoptosis in HL-60 cells through oxidative stress mechanisms[1]. |
In vitro | PAO exhibits IC50 values of 6.2 μM, 9.4 μM, 7.7 μM in HL-60, 7721 and Hela cells (48 h)[1]. |
分子量 | 509.394 |
分子式 | C24H24AsN3O5 |
CAS No. | 1613402-20-2 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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PAO-Nap 1613402-20-2 PAONap PAO Nap Inhibitor inhibitor inhibit