Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PARP-2-IN-3 is used as a potent PARP-2 inhibitor (IC50=0.07 μM) with anti-tumor activity that induces apoptosis and necrosis in cancer cells, and can be used for the study of breast cancer.CAS 번호128-52-56-8
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 80,500 |
5 mg | 在庫あり | ¥ 223,000 |
25 mg | 在庫あり | ¥ 365,000 |
50 mg | 在庫あり | ¥ 454,500 |
説明 | PARP-2-IN-3 is used as a potent PARP-2 inhibitor (IC50=0.07 μM) with anti-tumor activity that induces apoptosis and necrosis in cancer cells, and can be used for the study of breast cancer.CAS 번호128-52-56-8 |
ターゲット&IC50 | PARP2:0.07 μM |
In vitro | PARP-2-IN-3(Compound 12) has been demonstrated as the most potent PARP-2 inhibitor, with IC50 values of 0.07 µM. Compound 12 induces cell cycle arrest at the G2/M and G1/S phases in mutant MCF-7 cell line and exhibits significant apoptosis-inducing activity[1]. |
分子量 | 385.84 |
分子式 | C20H20ClN3O3 |
CAS No. | 2915650-86-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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PARP-2-IN-3 2915650-86-9 Apoptosis Chromatin/Epigenetic DNA Damage/DNA Repair PARP Inhibitor inhibitor inhibit