Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PCSK9 degrader 1 is a selective proprotein convertase substilisin-like/kexin type 9 (PCSK9) degrader. PCSK9 degrader 1 does not affect PCSK9 function.
説明 | PCSK9 degrader 1 is a selective proprotein convertase substilisin-like/kexin type 9 (PCSK9) degrader. PCSK9 degrader 1 does not affect PCSK9 function. |
In vitro | Biphenyl acid PCSK9 degrader 1 (compound 9) binds to and thermally stabilizes PCSK9 in a complex environment such as Huh7 lysate[1]. PCSK9 degrader 1 (compound 9), with high affinity for recombinant PCSK9 and target engagement in cell lysate, could be used as a recruiting element to promote the selective degradation of PCSK9[1]. |
分子量 | 631.72 |
分子式 | C34H34FN3O6S |
CAS No. | 2215931-60-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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PCSK9 degrader 1 2215931-60-3 PCSK-9 degrader 1 Inhibitor inhibitor inhibit