Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Potent EGFR-kinase inhibitor (IC50 = 0.7 nM). Displays >3000-fold selectivity against a panel of serine/threonine kinases. Reduces metastasis and angiogenesis in a mouse model of pancreatic cancer. Antihypertensive and orally bioavailable.
説明 | Potent EGFR-kinase inhibitor (IC50 = 0.7 nM). Displays >3000-fold selectivity against a panel of serine/threonine kinases. Reduces metastasis and angiogenesis in a mouse model of pancreatic cancer. Antihypertensive and orally bioavailable. |
ターゲット&IC50 | EGFR tyrosine kinase:0.7 nM (IC50) |
分子量 | 366.85 |
分子式 | C20H19ClN4O |
CAS No. | 2230253-82-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
You can also refer to dose conversion for different animals. 詳細
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PKI-166 hydrochloride 2230253-82-2 Others PKI166 Hydrochloride PKI-166 Hydrochloride PKI 166 hydrochloride PKI166 hydrochloride PKI 166 Hydrochloride Inhibitor inhibitor inhibit