Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PROTAC BRD4 Degrader-9 (compound 8a) is a novel chemical compound consisting of ligands for von Hippel-Lindau and BRD4, connected by a PROTAC moiety. This compound can effectively degrade the BRD4 protein in PC3 prostate cancer cells. When conjugated with STEAP1 and CLL1 antibodies, PROTAC BRD4 Degrader-9 exhibits potent activity, with respective DC50 values of 0.86 nM and 7.6 nM.
説明 | PROTAC BRD4 Degrader-9 (compound 8a) is a novel chemical compound consisting of ligands for von Hippel-Lindau and BRD4, connected by a PROTAC moiety. This compound can effectively degrade the BRD4 protein in PC3 prostate cancer cells. When conjugated with STEAP1 and CLL1 antibodies, PROTAC BRD4 Degrader-9 exhibits potent activity, with respective DC50 values of 0.86 nM and 7.6 nM. |
別名 | PROTAC BRD4 Degrader-9 |
分子量 | 1312.5 |
分子式 | C59H71F2N9O15S4 |
CAS No. | 2417370-42-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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PROTAC BRD4 Degrader-9 2417370-42-2 PROTAC BRD4 Degrader9 PROTAC BRD-4 Degrader-9 PROTAC BRD4 Degrader 9 Inhibitor inhibitor inhibit