Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Py-MAA-Val-Cit-PAB-MMAE (AAJ8D6-PY-Val-Cit-MMAE) serves as an ADC linker for Zapadcine-3a, a broad-spectrum anti-TRAILR2 ADC with antineoplastic properties. By targeting TRAILR2, Zapadcine-3a is internalized into the lysosomes of tumor cells, where it subsequently releases a small molecular compound that selectively eradicates TRAILR2-positive tumor cells, potentially leading to tumor remission [1].
説明 | Py-MAA-Val-Cit-PAB-MMAE (AAJ8D6-PY-Val-Cit-MMAE) serves as an ADC linker for Zapadcine-3a, a broad-spectrum anti-TRAILR2 ADC with antineoplastic properties. By targeting TRAILR2, Zapadcine-3a is internalized into the lysosomes of tumor cells, where it subsequently releases a small molecular compound that selectively eradicates TRAILR2-positive tumor cells, potentially leading to tumor remission [1]. |
別名 | AAJ8D6-PY-Val-Cit-MMAE |
分子量 | 1446.79 |
分子式 | C72H111N13O16S |
CAS No. | 2247398-68-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Py-MAA-Val-Cit-PAB-MMAE 2247398-68-9 Others AAJ8D6-PY-Val-Cit-MMAE Inhibitor inhibitor inhibit