Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid . [1] In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state.[2] Resolvin D5 (RvD5) is a DHA-derived resolvin generated by a double dioxygenation mechanism.[3] RvD5 has been identified in media from ionophore-stimulated trout brain cells, in human synovial fluid from patients with rheumatoid arthritis, and in exudates of bacterial infections in mice. [4][5][6] RvD5 stimulates the phagocytosis of E. coli by human macrophages, and RvD5 methyl ester enhances bacterial killing in mice inoculated with E. coli. [6] Analytical and biological comparisons of synthetic RvD5 with endogenously derived RvD5 have confirmed its identity as matching the natural product.[7]
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
10 μg | 約 35 days | ¥ 88,000 |
25 μg | 約 35 days | ¥ 203,500 |
50 μg | 約 35 days | ¥ 392,500 |
100 μg | 約 35 days | ¥ 686,500 |
説明 | Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid . [1] In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state.[2] Resolvin D5 (RvD5) is a DHA-derived resolvin generated by a double dioxygenation mechanism.[3] RvD5 has been identified in media from ionophore-stimulated trout brain cells, in human synovial fluid from patients with rheumatoid arthritis, and in exudates of bacterial infections in mice. [4][5][6] RvD5 stimulates the phagocytosis of E. coli by human macrophages, and RvD5 methyl ester enhances bacterial killing in mice inoculated with E. coli. [6] Analytical and biological comparisons of synthetic RvD5 with endogenously derived RvD5 have confirmed its identity as matching the natural product.[7] |
別名 | 7(S),17(S)-diHDHA |
分子量 | 360.494 |
分子式 | C22H32O4 |
CAS No. | 578008-43-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF: 50 mg/mL
Ethanol: 50 mg/mL
You can also refer to dose conversion for different animals. 詳細
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Resolvin D5 578008-43-2 Resolvin D-5 7(S),17(S)-diHDHA 7,17diHDHA Inhibitor inhibitor inhibit