Powder: -20°C for 3 years | In solvent: -80°C for 1 year
RET-IN-23 (compound 17) is a potent, orally active inhibitor of RET, displaying IC50 values of 1.32 nM for RET-WT, 2.50 nM for RET-CCDC6, 6.54 nM for RET-V804L, 1.03 nM for RET-V804M, and 1.47 nM for RET-M918T. The compound demonstrates significant anti-tumor activity [1].
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 349,000 |
50 mg | 約6-8 週間 | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
説明 | RET-IN-23 (compound 17) is a potent, orally active inhibitor of RET, displaying IC50 values of 1.32 nM for RET-WT, 2.50 nM for RET-CCDC6, 6.54 nM for RET-V804L, 1.03 nM for RET-V804M, and 1.47 nM for RET-M918T. The compound demonstrates significant anti-tumor activity [1]. |
In vivo | RET-IN-23 (5 mg/kg; oral administration) demonstrated antitumor activity in mice [1]. |
分子量 | 537.59 |
分子式 | C28H28FN11 |
CAS No. | 2479961-46-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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RET-IN-23 2479961-46-9 Inhibitor inhibitor inhibit