Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Reveromycin A is the major component of a complex of spiroketal antibiotics isolated from Streptomyces sp. It inhibits the mitogenic activity of epidermal growth factor in Balb/MK cells (IC50 = 0.7 μg/ml), displays antiproliferative activity against human KB and K562 tumor cell lines (IC50s = 1.9 and 1.6 μg/ml, respectively), and demonstrates antifungal activity against C. albicans (MIC = 2 μg/ml at pH 3). Reveromycin A also has been shown to inhibit bone resorption by inducing apoptosis in osteoclasts with an IC50 value of 0.7 μM.
説明 | Reveromycin A is the major component of a complex of spiroketal antibiotics isolated from Streptomyces sp. It inhibits the mitogenic activity of epidermal growth factor in Balb/MK cells (IC50 = 0.7 μg/ml), displays antiproliferative activity against human KB and K562 tumor cell lines (IC50s = 1.9 and 1.6 μg/ml, respectively), and demonstrates antifungal activity against C. albicans (MIC = 2 μg/ml at pH 3). Reveromycin A also has been shown to inhibit bone resorption by inducing apoptosis in osteoclasts with an IC50 value of 0.7 μM. |
分子量 | 660.79 |
分子式 | C36H52O11 |
CAS No. | 134615-37-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Methanol: Soluble
DMSO: Soluble
Ethanol: Soluble
DMF: Soluble
You can also refer to dose conversion for different animals. 詳細
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Reveromycin A 134615-37-5 Inhibitor inhibitor inhibit