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Rilotumumab (AMG 102) is a monoclonal antibody targeting hepatocyte growth factor that inhibits HGF/ MET-driven signaling. Rilotumumab has antitumor effects and can be used to study castration-resistant prostate cancer (CRPC) and gastric cancer.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 58,500 |
5 mg | 在庫あり | ¥ 153,500 |
10 mg | 在庫あり | ¥ 245,500 |
25 mg | 在庫あり | ¥ 363,000 |
50 mg | 在庫あり | ¥ 489,000 |
100 mg | 在庫あり | ¥ 661,000 |
説明 | Rilotumumab (AMG 102) is a monoclonal antibody targeting hepatocyte growth factor that inhibits HGF/ MET-driven signaling. Rilotumumab has antitumor effects and can be used to study castration-resistant prostate cancer (CRPC) and gastric cancer. |
In vitro | In an overnight treatment at 10 μg/mL, Rilotumumab induces a decrease in MET phosphorylation at Y1234 and Y1235, accompanied by an increase in total MET[2]. |
In vivo | In vivo, treatment with Rilotumumab (intraperitoneal injection; 1.5 mg/kg; once every two days; for 11 days) inhibits glioma cell growth[2]. |
別名 | AMG 102 |
分子量 | N/A |
CAS No. | 872514-65-3 |
store at low temperature
store at -80°C
You can also refer to dose conversion for different animals. 詳細
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Rilotumumab 872514-65-3 Tyrosine Kinase/Adaptors c-Met/HGFR AMG102 AMG-102 AMG 102 Inhibitor inhibitor inhibit