Powder: -20°C for 3 years | In solvent: -80°C for 1 year
RTIL 13 is a highly effective inhibitor of dynamin GTPase, exhibiting an IC50 value of 2.3 μM for dynamin I GTPase. Furthermore, it selectively interacts with the pleckstrin homology lipid binding domain. This compound effectively suppresses both receptor-mediated and synaptic vesicle endocytosis, demonstrating IC50 values of 9.3 μM and 7.1 μM, respectively.
説明 | RTIL 13 is a highly effective inhibitor of dynamin GTPase, exhibiting an IC50 value of 2.3 μM for dynamin I GTPase. Furthermore, it selectively interacts with the pleckstrin homology lipid binding domain. This compound effectively suppresses both receptor-mediated and synaptic vesicle endocytosis, demonstrating IC50 values of 9.3 μM and 7.1 μM, respectively. |
ターゲット&IC50 | Dynamin I GTPase:2.3 µM (IC50) |
In vitro | RTIL 13 effectively inhibits receptor-mediated and synaptic vesicle endocytosis, demonstrating inhibition concentrations (IC50s) of 9.3 μM and 7.1 μM, respectively[2]. |
分子量 | 571.685 |
分子式 | C30H55BrN2O3 |
CAS No. | 1009376-10-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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RTIL 13 1009376-10-6 RTIL13 RTIL-13 Inhibitor inhibitor inhibit