keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shepherdin is a synthetic peptide mirroring amino acids 79-87 of human survivin, acting as an inhibitor of the survivin-heat shock protein 90 (Hsp90) interaction. It specifically targets the N-terminal domain of Hsp90, blocking the survivin-Hsp90 interaction in human reticulocyte extracts at a 150 µM concentration. Conjugates of Shepherdin with cell-permeable peptides, such as penetratin or the HIV Tat sequence, exhibit anticancer properties both in vitro and in vivo.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | お問い合わせ | ¥ 13,000 |
5 mg | お問い合わせ | ¥ 45,500 |
10 mg | お問い合わせ | ¥ 86,500 |
25 mg | お問い合わせ | ¥ 181,000 |
説明 | Shepherdin is a synthetic peptide mirroring amino acids 79-87 of human survivin, acting as an inhibitor of the survivin-heat shock protein 90 (Hsp90) interaction. It specifically targets the N-terminal domain of Hsp90, blocking the survivin-Hsp90 interaction in human reticulocyte extracts at a 150 µM concentration. Conjugates of Shepherdin with cell-permeable peptides, such as penetratin or the HIV Tat sequence, exhibit anticancer properties both in vitro and in vivo. |
別名 | Lys-His-Ser-Ser-Gly-Cys-Ala-Phe-Leu-OH, Survivin (79-87) |
分子量 | 949.10 |
分子式 | C41H64N12O12S.XCF3COOH |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: Soluble
Methanol: Soluble
You can also refer to dose conversion for different animals. 詳細
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Shepherdin TFA Lys-His-Ser-Ser-Gly-Cys-Ala-Phe-Leu-OH Survivin (79-87) Inhibitor inhibitor inhibit