Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SHP2-IN-14 (compound 27) is a potent, orally active allosteric inhibitor of SHP2, displaying strong anti-tumor activity with an IC50 of 7 nM. It inhibits tumor progression in NCI-H358 tumor-bearing mice and demonstrates favorable pharmacokinetic properties and safety [1].
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約8-10 週間 | ¥ 452,500 |
50 mg | 約8-10 週間 | ¥ 592,500 |
100 mg | 約8-10 週間 | ¥ 780,500 |
説明 | SHP2-IN-14 (compound 27) is a potent, orally active allosteric inhibitor of SHP2, displaying strong anti-tumor activity with an IC50 of 7 nM. It inhibits tumor progression in NCI-H358 tumor-bearing mice and demonstrates favorable pharmacokinetic properties and safety [1]. |
分子量 | 483.35 |
分子式 | C22H20Cl2N8O |
CAS No. | 2673400-91-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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SHP2-IN-14 2673400-91-2 Inhibitor inhibitor inhibit