Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SKI-I is a potent and selective inhibitor of human sphingosine kinase (SK). SKI-I shows an IC 50 of 1.2 μM for ST-hSK. SKI-I is also a hERK2 inhibitor( IC 50 =11 μM). SKI-I induces apoptosis in tumor cell lines.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 210,500 |
50 mg | 約6-8 週間 | ¥ 273,500 |
100 mg | 約6-8 週間 | ¥ 427,000 |
説明 | SKI-I is a potent and selective inhibitor of human sphingosine kinase (SK). SKI-I shows an IC 50 of 1.2 μM for ST-hSK. SKI-I is also a hERK2 inhibitor( IC 50 =11 μM). SKI-I induces apoptosis in tumor cell lines. |
In vitro | SKI-I (Compound I; 5 μg/mL) effectively suppresses SK activity by 99% [1]. Additionally, at a concentration of 10 μM and over a period of 24 hours, SKI-I promotes apoptosis in T24 cells [1]. |
分子量 | 406.44 |
分子式 | C25H18N4O2 |
CAS No. | 306301-68-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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SKI-I 306301-68-8 Inhibitor inhibitor inhibit