Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Spilanthol, an orally active compound with analgesic, neuroprotective, antioxidant, antimutagenic, anti-cancer, anti-inflammatory, antimicrobial, and insecticidal properties, facilitates the induction of cAMP, thereby inhibiting the negative regulation of the urinary concentration mechanism. It is also utilized in diuretic research [1] [4] [5].
説明 | Spilanthol, an orally active compound with analgesic, neuroprotective, antioxidant, antimutagenic, anti-cancer, anti-inflammatory, antimicrobial, and insecticidal properties, facilitates the induction of cAMP, thereby inhibiting the negative regulation of the urinary concentration mechanism. It is also utilized in diuretic research [1] [4] [5]. |
In vitro | Spilanthol (50~150 μM, 24h) has no effect on the viability of A549 human lung epithelial cells [3]. |
In vivo | Spilanthol (1-1.875 mg/kg, IP, once) exhibited analgesic effects in male ICR mouse models induced by acetic acid writhing and capsaicin paw licking [2]. Spilanthol (30 mg/kg, orally, once daily for four days) protected against intestinal mucositis in Swiss mice induced by 5-Fluorouracil [4]. Additionally, Spilanthol (800 mg/kg, orally, administered once) acted as a diuretic in adult male C57BL/6J mice [5]. |
分子量 | 221.34 |
分子式 | C14H23NO |
CAS No. | 25394-57-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Spilanthol 25394-57-4 Inhibitor inhibitor inhibit