store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Suzetrigine(VX-548) is an orally active and specific NaV1.8 inhibitor. Suzetrigine has analgesic activity and can be used to study acute pain and neurotransmission.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 110,000 |
5 mg | 在庫あり | ¥ 271,000 |
10 mg | 在庫あり | ¥ 363,000 |
25 mg | 在庫あり | ¥ 539,500 |
50 mg | 在庫あり | ¥ 730,000 |
説明 | Suzetrigine(VX-548) is an orally active and specific NaV1.8 inhibitor. Suzetrigine has analgesic activity and can be used to study acute pain and neurotransmission. |
In vivo | As compared with placebo, VX-548 at the highest dose (a 100-mg oral loading dose of VX-548, followed by a 50-mg maintenance dose every 12 hours), but not at lower doses (a 20-mg loading dose, followed by a 10-mg maintenance dose every 12 hours), reduced acute pain over a period of 48 hours after abdominoplasty or bunionectomy.[1] |
別名 | VX-548 |
分子量 | 473.39 |
分子式 | C21H20F5N3O4 |
CAS No. | 2649467-58-1 |
store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (211.24 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Suzetrigine 2649467-58-1 Membrane transporter/Ion channel Sodium Channel VX-548 VX 548 VX548 Inhibitor inhibitor inhibit