Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SZUH280 is a potent, selective PROTAC (proteolysis targeting chimera) HDAC8 (histone deacetylase 8) degrader, demonstrating a DC50 of 0.58 μM in A549 cells. It induces apoptosis in cancer cells and impedes DNA damage repair, thereby enhancing cellular radiosensitization [1].
説明 | SZUH280 is a potent, selective PROTAC (proteolysis targeting chimera) HDAC8 (histone deacetylase 8) degrader, demonstrating a DC50 of 0.58 μM in A549 cells. It induces apoptosis in cancer cells and impedes DNA damage repair, thereby enhancing cellular radiosensitization [1]. |
分子量 | 706.7 |
分子式 | C36H34N8O8 |
CAS No. | 2770263-77-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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SZUH280 2770263-77-7 Inhibitor inhibitor inhibit