Powder: -20°C for 3 years | In solvent: -80°C for 1 year
T-5342126 is a toll-like receptor 4 (TLR4) antagonist.1It reduces LPS-induced production of nitric oxide (NO) in RAW 264.7 cells (IC50= 27.8 μM), as well as decreases LPS-induced IL-8, TNF-α, and IL-6 production in isolated human whole blood (IC50s = 110.5, 315.6, and 318.4 μM, respectively). T-5342126 (82 mg/kg) reduces ethanol intake and the abundance of ionized calcium-binding adapter molecule 1 (Iba1), a marker of microglial activation, in the central nucleus of the amygdala in ethanol-dependent mice.2
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 約 35 days | ¥ 33,000 |
5 mg | 約 35 days | ¥ 134,000 |
10 mg | 約 35 days | ¥ 226,500 |
説明 | T-5342126 is a toll-like receptor 4 (TLR4) antagonist.1It reduces LPS-induced production of nitric oxide (NO) in RAW 264.7 cells (IC50= 27.8 μM), as well as decreases LPS-induced IL-8, TNF-α, and IL-6 production in isolated human whole blood (IC50s = 110.5, 315.6, and 318.4 μM, respectively). T-5342126 (82 mg/kg) reduces ethanol intake and the abundance of ionized calcium-binding adapter molecule 1 (Iba1), a marker of microglial activation, in the central nucleus of the amygdala in ethanol-dependent mice.2 |
分子量 | 457.99 |
分子式 | C25H32ClN3O3 |
CAS No. | 956507-49-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Methyl Acetate: 10 mg/mL
You can also refer to dose conversion for different animals. 詳細
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T-5342126 956507-49-6 T 5342126 T5342126 Inhibitor inhibitor inhibit