Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tandutinib hydrochloride (MLN518 hydrochloride) is a potent, selective FLT3 inhibitor with an IC50 of 0.22 μM. It also effectively inhibits c-Kit and PDGFR, with IC50 values of 0.17 μM and 0.20 μM, respectively. This compound is clinically applicable for treating acute myelogenous leukemia (AML) and possesses the capability to cross the blood-brain barrier.
説明 | Tandutinib hydrochloride (MLN518 hydrochloride) is a potent, selective FLT3 inhibitor with an IC50 of 0.22 μM. It also effectively inhibits c-Kit and PDGFR, with IC50 values of 0.17 μM and 0.20 μM, respectively. This compound is clinically applicable for treating acute myelogenous leukemia (AML) and possesses the capability to cross the blood-brain barrier. |
分子量 | 599.16 |
分子式 | C31H43ClN6O4 |
CAS No. | 2438900-70-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Tandutinib hydrochloride 2438900-70-8 Inhibitor inhibitor inhibit