Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Thalidomide-NH-C8-NH2 is a synthetic conjugate of an E3 ligase ligand-linker, which combines a cereblon ligand based on Thalidomide with a specific linker utilized in PROTAC technology.
説明 | Thalidomide-NH-C8-NH2 is a synthetic conjugate of an E3 ligase ligand-linker, which combines a cereblon ligand based on Thalidomide with a specific linker utilized in PROTAC technology. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
別名 | Thalidomide-NH-C8-NH2 |
分子量 | 400.479 |
分子式 | C21H28N4O4 |
CAS No. | 1957236-36-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Thalidomide-NH-C8-NH2 1957236-36-0 Thalidomide NH C8 NH2 Thalidomide-NH-C-8-NH2 ThalidomideNHC8NH2 Inhibitor inhibitor inhibit