store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TREM2 agonist-2 (I-192) is an orally active and potent myeloid triggered receptor 2 (TREM2) agonist for the study of neurodegenerative diseases.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 65,000 |
5 mg | 在庫あり | ¥ 160,500 |
10 mg | 在庫あり | ¥ 266,500 |
25 mg | 在庫あり | ¥ 489,000 |
50 mg | 在庫あり | ¥ 638,000 |
100 mg | 在庫あり | ¥ 808,000 |
説明 | TREM2 agonist-2 (I-192) is an orally active and potent myeloid triggered receptor 2 (TREM2) agonist for the study of neurodegenerative diseases. |
In vitro | Treatment with TREM2 agonist-2 (0-100μM; 16 hours) activated hTREM2 in HEK293 cells, with an EC50 value less than 0.05μM for cell viability assay[1]. |
In vivo | The results indicate that TREM2 agonist-2 (50 mg/kg; twice daily; oral gavage for one day) can bind to the TREM2 target, which can interact with microglial cells[1]. |
分子量 | 451.92 |
分子式 | C24H23ClFN5O |
CAS No. | 2738485-98-6 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45.19 mg/mL (100 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
TREM2 agonist-2 2738485-98-6 Others Inhibitor inhibitor inhibit