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Tremelimumab is a cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) blocking antibody.Tremelimumab is often used in combination with Durvalumab for the treatment of solid cancers such as hepatocellular carcinoma and lung cancer.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 35,500 |
5 mg | 在庫あり | ¥ 108,500 |
10 mg | 在庫あり | ¥ 158,500 |
25 mg | 在庫あり | ¥ 248,000 |
50 mg | 在庫あり | ¥ 335,000 |
100 mg | 在庫あり | ¥ 452,500 |
説明 | Tremelimumab is a cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) blocking antibody.Tremelimumab is often used in combination with Durvalumab for the treatment of solid cancers such as hepatocellular carcinoma and lung cancer. |
In vitro | Tremelimumab exhibits a higher binding affinity for CTLA-4-Ig compared to CD28-Ig, demonstrating specificity for cynomolgus monkeys and humans. It does not engage with human leukocyte FcγR, mitigating the risk of cytokine release syndrome. Interestingly, Tremelimumab enhances IL-2 production in a concentration-dependent manner when stimulated with staphylococcal enterotoxin A, showcasing its ability to modulate T-cell responses.[1] |
別名 | Ticilimumab, CP-675206 |
分子量 | N/A |
CAS No. | 745013-59-6 |
store at low temperature
store at -20°C
You can also refer to dose conversion for different animals. 詳細
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Tremelimumab 745013-59-6 Others Ticilimumab CP 675206 CP675206 CP-675206 Inhibitor inhibitor inhibit