Powder: -20°C for 3 years | In solvent: -80°C for 1 year
UNC2399, a biotinylated version of UNC1999, functions as a selective degrader of EZH2 and exhibits strong in vitro efficacy against EZH2, demonstrated by its IC 50 value of 17 nM.
説明 | UNC2399, a biotinylated version of UNC1999, functions as a selective degrader of EZH2 and exhibits strong in vitro efficacy against EZH2, demonstrated by its IC 50 value of 17 nM. |
ターゲット&IC50 | EZH2:17 nM (IC50) |
In vitro | UNC2399, at concentrations ranging from 1 to 1000 nM, demonstrates significant in vitro efficacy with an IC50 value of 17±2 nM in the EZH2 radioactive biochemical assay[1]. Additionally, at a concentration of 100 μM, UNC2399 successfully enriches EZH2 from HEK293T cell lysates[1]. |
別名 | UNC2399 |
分子量 | 1353.68 |
分子式 | C67H104N10O17S |
CAS No. | 2412791-72-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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UNC2399 2412791-72-9 UNC 2399 UNC-2399 Inhibitor inhibitor inhibit