Powder: -20°C for 3 years | In solvent: -80°C for 1 year
VEGFR2-IN-1 is a selective and potent VEGFR2 inhibitor with antitumor activity that inhibits cell proliferation and migration and can be used in the study of breast cancer.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 67,500 |
5 mg | 在庫あり | ¥ 166,000 |
10 mg | 在庫あり | ¥ 226,500 |
25 mg | 在庫あり | ¥ 349,000 |
50 mg | 在庫あり | ¥ 454,500 |
100 mg | 在庫あり | ¥ 574,000 |
説明 | VEGFR2-IN-1 is a selective and potent VEGFR2 inhibitor with antitumor activity that inhibits cell proliferation and migration and can be used in the study of breast cancer. |
ターゲット&IC50 | MCF - 10A:24.76 μM, VEGFR2:19.8 nM, MCF-7 cells:1.18 μM, 1.18 μM:MDA - MB - 231 |
In vitro | VEGFR2-IN-1 ( 0.1,1,10,100μM ; 48 h ) were effective selective inhibitors of Mcf-7, Mda-Mb-231 and Mcf-10A : MCF-7 ( IC50 = 1.18 μM ), MDA-MB-231 ( IC50 = 10.49 μM ), MCF-10A ( IC50 = 24.76 μM )[1]. |
In vivo | In Male Swiss albino mice, 21-28 g ( Xenograft model ),VEGFR2-IN-1 ( 4.2 mg/kg; i.p.; once a days ; 7 days ) Showed anticancer activity by having a tumor inhibition ratio of 54.2 % [1]. |
分子量 | 398.48 |
分子式 | C22H18N6S |
CAS No. | 2765224-55-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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VEGFR2-IN-1 2765224-55-1 Angiogenesis Tyrosine Kinase/Adaptors VEGFR Inhibitor inhibitor inhibit