The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents. 3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33 KDa and the accession number is P0DTC1.
| 説明 |
The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents. 3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33 KDa and the accession number is P0DTC1. |
| Species |
2019-nCoV
|
| Expression Host |
E. coli
|
| Tag |
N-6His
|
| Accession Number |
P0DTC1
|
| 別名 |
M Proteinase, 3CL Proteinase
|
| Amino Acid |
Ser3264-Gln3569
|
| Construction |
Recombinant 2019-nCoV 3C-like Proteinase is produced by our E.coli expression system and the target gene encoding Ser3264-Gln3569 is expressed with a 6His tag at the N-terminus
|
| Protein Purity |
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
|
| 分子量 |
33 KDa, reducing conditions
|
| Formulation |
Supplied as a 0.2 μm filtered solution of PBS, 1mM EDTA, 10% Glycerol, pH 7.4.
|
| Stability & Storage |
Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.
|
| Shipping |
The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below.
|
| Research Background |
The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents.
|
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