4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 30 KDa and the accession number is P41273.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
10 μg | 約5 days | ¥ 20,000 |
50 μg | 約5 days | ¥ 60,500 |
500 μg | 約5 days | ¥ 493,500 |
1 mg | 約5 days | ¥ 739,000 |
説明 | 4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 30 KDa and the accession number is P41273. |
Species | Human |
Expression Host | HEK293 Cells |
Tag | N-6xHis-Flag |
Accession Number | P41273 |
別名 | Tumor necrosis factor ligand superfamily member 9, 4-1BBL, TNFSF9, 4-1BB ligand |
Amino Acid | Arg71-Glu254 |
Construction | Arg71-Glu254 |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 30 KDa (reducing condition) |
Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 500 mM NaCl, 5% Trehalose, 5% Mannitol, 0.01% Tween 80, 1 mM EDTA, pH8.0. |
Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Stability & Storage |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | Tumor necrosis factor ligand superfamily member 9(4-1BBL) is single-pass type II membrane protein which is a member of the the tumor necrosis factor family. 4-1BBL is a 254 amino acids cytokine that is expressed in brain, placenta, lung, skeletal muscle and kidney. TNFSF9 has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine may have a role in activation-induced cell death (AICD) and cognate interactions between T-cells and B-cells/macrophages. It has also been shown to be required for the optimal CD8 responses in CD8 T cells, and is thought to be involved in T cell-tumor cell interaction. |
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Please read the User Guide of Recombinant Proteins for more specific information.
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag) TNFSF 9 TNFSF-9 Tumor necrosis factor ligand superfamily member 9 4-1BBL TNFSF9 4-1BB ligand recombinant recombinant-proteins proteins protein